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Pregnancy: Felodipine should not be given during pregnancy. In non-clinical reproductive toxicity studies there were foetal developmental effects, which are considered to be due to the pharmacological action of felodipine.
Breastfeeding: Felodipine has been detected in breastmilk, and due to insufficient data on potential effect on the infant, treatment is not recommended during breastfeeding.
Fertility: There are no data on the effects of felodipine on patient fertility. In a nonclinical reproductive study in the rat (see Pharmacology: Toxicology: Preclinical Safety Data under Actions), there were effects on foetal development but no effect on fertility at doses approximating to therapeutic.
